Biochemical Composition of Lymphocytic Choriomeningitis Virus Interfering Particles
نویسندگان
چکیده
منابع مشابه
The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles
Arenaviruses cause severe diseases in humans but establish asymptomatic, lifelong infections in rodent reservoirs. Persistently-infected rodents harbor high levels of defective interfering (DI) particles, which are thought to be important for establishing persistence and mitigating virus-induced cytopathic effect. Little is known about what drives the production of DI particles. We show that ne...
متن کاملLymphocytic Choriomeningitis Virus
There has been an upsurge of interest in lymphocytic choriomeningitis virus (LCMV) as a human pathogen and specifically as an underdiagnosed congenital infection (1,2). LCMV is a member of the Arenaviridae family of viruses. Arenaviruses have a complex life cycle involving chronic infection and shedding of the virus in rodents and episodic infections in humans (3,4). Six of the arenaviruses (La...
متن کاملEncephalitis Syndrome of Lymphocytic Choriomeningitis Virus Infection.
Studies on Eaton PPLO Pneumonia ELLI JANSSON, 0. WAGER, R. STENSTROM, E. KLEMOLA, AND P. FORSSELL ... ... ... ... 142 Sensitivities of Colonies and Suspensions of Actinomyces Israelii to Penicillins, Tetracyclines, and Erythromycin G. C. BLAKE ... ... ... ... 145 Comparison of Ampicillin and Chloramphenicol in Treatment of Paratyphoid Fever R. A. SLEET, G. SANGSTER, AND J. MCC. MURDOCH ... ... ...
متن کاملAn interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis.
Previous studies have documented that, in the presence of the mutagenic base analogue 5-fluorouracil (FU), lymphocytic choriomeningitis virus (LCMV) that persisted in BHK-21 cells decreased its infectivity to a larger extent than intracellular viral RNA levels, prior to virus extinction. This observation, together with in silico simulations, led to the proposal of the lethal defection model of ...
متن کاملHuman Infection with Lymphocytic Choriomeningitis Virus
Lung contusions and pandemic (H1N1) 2009 can cause ARDS (6,7). We do not know the relative role of each in causing the ARDS that our patient had, but the severity of clinical symptoms, although the lung injury was judged to be only of moderate magnitude, suggests that infl uenza played a major role in the development of his acute lung disease. The infection with oseltamivir-resistant virus, for...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1981
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-55-2-475